Hyatt Regency San Francisco

The Hyatt Regency San Francisco near the Embarcadero center functions great as a business hotel with its many meeting rooms and large halls. Boasting the world's largest lobby, it also has great views of the pier (although mine was a partial one off my balcony). I especially appreciated the hallway water cooler and gym dumbells that go up to 75 lbs, a rarity for hotel gyms. Pictures below are from the View Balcony Room which features a private balcony. If you're looking for a more leisurely stay though with friendlier you're-not-just-another-suit service, I'd tend more towards Starwood's San Francisco offerings (the W is one of my favorites).